The retinoblastoma protein (pRb) is a cell cycle regulator inactivated in most human cancers.Loss of pRb function results from mutations in the gene coding for pRb or for any of its upstream regulators.Although pRb is predominantly known as a cell cycle repressor, our data point to additional pRb functions in cell adhesion.Our data show that pRb re
Spatial Footprints of Human Perceptual Experience in Geo-Social Media
Analyses of social media have increased in importance for understanding human behaviors, interests, and opinions.Business intelligence based on social media can reduce the costs of managing customer trend complexities.This paper focuses on analyzing sensation information representing human perceptual W Boots experiences in social media through the
Routing Protocol for Intelligent Unmanned Cluster Network Based on Node Energy Consumption and Mobility Optimization
Intelligent unmanned clusters have played a crucial role in military reconnaissance, disaster rescue, border patrol, and other domains.Nevertheless, due to factors such as multipath propagation, electromagnetic interference, and frequency band congestion in high dynamic scenarios, unmanned cluster networks experience frequent topology changes and s
An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
Summary: Midbrain dopaminergic neurons (DANs) are subject to extensive metabotropic regulation, but the repertoire of G protein-coupled receptors (GPCRs) present in these neurons has not been mapped.Here, we isolate DANs from Dat-eGFP mice to generate a 125 GPCR atlas by unbiased qPCR array expression analysis of 377 GPCRs.Combined with data mining
Dressing, seducing and signifying: from the symbolic dimension of fashion to the contemporary erotic imagery
As a relatively recent social and cultural phenomenon, fashion currently embodies a certain erotic imagery that seems to organise collective life.According to Lipovetsky, it governs our societies.Fashion, being ephemeral by nature, actually expresses Depilatory Blades the sovereignty of appearance and the power of aesthetic fantasy.It is, in fact,